Description
Product Characteristics: antibody, TRPC4AP antibody, Chromosome 20 open reading frame 188 antibody, Protein TAP1 antibody, Protein TRUSS antibody, Short transient receptor potential channel 4 associated protein antibody, Short transient receptor potential channel 4-associated protein antibody, TAP1 protein antibody, TNF receptor ubiquitous scaffolding/signaling protein antibody, TNF-receptor ubiquitous scaffolding/signaling protein antibody, TP4AP_HUMAN antibody, Transient receptor potential cation channel, subfamily C, member 4 associated protein antibody, Trp4 associated protein antibody, Trp4-associated protein antibody, Trpc4 associated protein antibody, Trpc4-associated protein antibody, TRPC4AP antibody, TRRP4AP antibody, TRUSS antibody, Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein antibody
Target Information: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1